No, you do not want to mix it with a medication, the medication could definitely harm the sensitive bacteria. You want to wait until your treatment is done, then do a 25% water change and put fresh carbon in your filter to help pull the remaining medication out. Wait another 24 hours after this, and treat with TSS. As long as you did not add a lot of fish, the cycling should progress slowly enough that you can wait a few days before using TSS. If you are already registering ammonia, it may be better to sacrifice the one fish, and add TSS, as long as the ammonia is still low. Keep in mind, TSS is NOT a chemical, so it takes several days to start seeing results, and approximately 10-14 days for it to cycle a tank. Without TSS, it takes 4-8 weeks to cycle a tank.
answered 7 months ago
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